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Effects of inhibitory rTMS on bladder function in Parkinson's disease patients

✍ Scribed by Livia Brusa; Enrico Finazzi Agrò; Filomena Petta; Francesco Sciobica; Sara Torriero; Emanuele Lo Gerfo; Cesare Iani; Paolo Stanzione; Giacomo Koch

Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
905 KB
Volume
24
Category
Article
ISSN
0885-3185

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✦ Synopsis

Abstract

Patients affected by Parkinson's disease (PD) may present with lower urinary tract (LUT) dysfunction characterized by involuntary detrusor overactivity. We evaluated possible impact of a 2‐week course of low frequency 1 Hz repetitive transcranial magnetic stimulation (rTMS) on LUT behavior in eight advanced PD patients complaining of urinary disturbances. We tested the effects of rTMS measuring urodynamic examination and the International Prostate Symptoms Score (IPSS) questionnaire, used for evaluation of subjective LUTS. rTMS was able to improve temporarily LUT behavior in PD patients, increasing bladder capacity and the first sensation of filling phase. Moreover, a reduction of IPSS score was noticed, due to an improvement on filling phase symptoms. The beneficial effects assessed with the IPSS lasted for up to 2 weeks after the end of the stimulation. rTMS seems to be an effective, noninvasive alternative treatment for PD patients with urinary disturbances. © 2009 Movement Disorder Society

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