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Effects of inhibition of PDE4 and TNF-α on local and remote injuries following ischaemia and reperfusion injury

✍ Scribed by Danielle G Souza; Geovanni D Cassali; Steve Poole; Mauro M Teixeira

Book ID
110005941
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
225 KB
Volume
134
Category
Article
ISSN
0007-1188

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## Abstract __Introduction__: Tissues subjected to prolonged ischaemia are paradoxically further damaged when their perfusion is restored. The mechanisms underlying this ischaemia–reperfusion injury are complex, but oxidative attack is a central feature. Among the therapeutic agents used to attenua