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Effects of an α-tocopherol analogue on myocardial ischaemia and reperfusion injury in rats

✍ Scribed by Margaret Petty; J. Martin Grisar; James Dow; Wybren De Jong

Book ID
115883316
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
143 KB
Volume
179
Category
Article
ISSN
0014-2999

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Aminoguanidine is an inhibitor of nitric oxide synthase (NOS), with high selectivity for the inducible isoform (iNOS). In addition to being an inhibitor of NOS, aminoguanidine also exhibits antioxidant activity. Recent studies suggest that aminoguanidine reduces ischaemia-reperfusion (I/R)-induced d