𝔖 Bobbio Scriptorium
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Effects of indomethacin on bone ingrowth

✍ Scribed by Dr. J. C. Keller; T. M. Trancik; F. A. Young; E. St. Mary

Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
697 KB
Volume
7
Category
Article
ISSN
0736-0266

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✦ Synopsis

The effects of indomethacin, a nonsteriodal antiinflammatory agent, on bone ingrowth were studied using a rabbit animal model and a porous cylindrical implant system. Bone ingrowth was found to be independent of pore size in the range tested (0.6-1.0 mm). In the control (placebo-treated) group, there was a significant increase in bone ingrowth between the 2-and 8-week groups of animals. However, in the indomethacin-treated group, there was no increase in bone ingrowth with time.

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