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Effects of in utero exposure to di-n-hexyl phthalate on testosterone synthesis in fetal rat testis

✍ Scribed by Anne-Marie Saillenfait; Alain Robert; Jean-Philippe Sabaté; Flavien Denis; Virginie Rouiller-Fabre; Delphine Moison; Frédéric Gallissot

Book ID: 113875966
Publisher: Elsevier Science
Year: 2011
Tongue: English
Weight: 68 KB
Volume: 32
Category: Article
ISSN: 0890-6238
DOI: 10.1016/j.reprotox.2011.06.099

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## Abstract Adult male rats gestationally exposed to di(n‐butyl)phthalate (DBP) have dysgenetic testes characterized by seminiferous epithelial degeneration, clustering of Leydig cells, and decreased spermatogenesis. Cell proliferation and apoptosis are key processes regulating development of the t