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EFFECTS OF HYPOXIA/REPERFUSION INJURY ON DRUG DISPOSITION IN THE RAT ISOLATED PERFUSED LIVER

โœ Scribed by HA Arab; K Cheung; PE Hickman; JM Potter; M Kadkhodaee; MS Roberts


Book ID
108937960
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
161 KB
Volume
34
Category
Article
ISSN
0305-1870

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๐Ÿ“œ SIMILAR VOLUMES


Differential Effects of Hypoxia on the D
โœ D. Brian Jones; George W. Mihaly; Richard A. Smallwood; Lorraine K. Webster; Den ๐Ÿ“‚ Article ๐Ÿ“… 1984 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 715 KB

Although the adverse effect of hypoxia on drug metabolism is well documented in subcellular systems, its effect on drug clearance by the intact liver has not been defined. This study was undertaken in the isolated perfused rat liver to examine the effects of acute hypoxia on the hepatic elimination