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Effects of hypothyroidism on insulin-like growth factor-I expression during brain development in mice

✍ Scribed by Deborah A Elder; Aysen F Karayal; A.Joseph D'Ercole; Ali S Calikoglu


Book ID
117471159
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
121 KB
Volume
293
Category
Article
ISSN
0304-3940

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Background: Insulin-like growth factor-I (IGF-I) is a peptide growth factor whose biological effects are mediated through a specific receptor (IGF-IR). IGF-I and IGF-IR are detected in both fetal and adult kidneys and have both metabolic and growth effects. IGF-IR expression during postnatal kidney