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Effects of hydroxysterols and atorvastatin on lipopolysaccharide-induced secretion of tumor necrosis factor and interleukin-10 by mouse macrophages

✍ Scribed by M. I. Dushkin; O. M. Khoshchenko; E. N. Kudinova; Ya. Sh. Schwartz


Publisher
Springer US
Year
2006
Tongue
English
Weight
255 KB
Volume
141
Category
Article
ISSN
0007-4888

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This work demonstrates the need for the continued presence of lipopolysaccharide (LPS) for tumor necrosis factor (TNF) production by thioglycollate-induced peritoneal macrophages. Removal of LPS at any time resulted in the abrupt cessation of further TNF production. The readdition of LPS resulted in