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Effects of human recombinant IL-1 and TNF on proteoglycan breakdown in cultured chondrocytes

โœ Scribed by T. Ikebe; H. Iribe; T. Koga


Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
82 KB
Volume
10
Category
Article
ISSN
0192-0561

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EFFECTS OF INTERLEUKIN-6 ON PROLIFERATIO
โœ Akitoshi Jikko; Takashi Wakisaka; Masahiro Iwamoto; Hiroko Hiranuma; Yukio Kato; ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 204 KB

Interleukin-6 (IL-6) levels are markedly increased in the synovial fluid of patients with rheumatoid arthritis or osteoarthritis. However, the effects of IL-6 on proliferation and proteoglycan metabolism in articular cartilage are not known. We demonstrated here the effects of human recombinant (hr)