Effects of highly overdosed indomethacin in a preterm infant with symptomatic patent ductus arteriosus
β Scribed by V. Schuster; H. B. von Stockhausen; H. W. Seyberth
- Publisher
- Springer
- Year
- 1990
- Tongue
- English
- Weight
- 290 KB
- Volume
- 149
- Category
- Article
- ISSN
- 0340-6997
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Indomethacin has proven effective in closing the patent ductus arteriosus (PDA) in most low birth weight (LBW) neonates with this disorder. Early reopening of the ductus is a problem and often leads to the need for surgery. Prolonged use of indomethacin for several days has been suggested as a means
First results are described of individually tailored indomethacin dose rates employing on-line drug level monitoring for pharmacologically induced ductal constriction in very low birth weight infants with symptomatic patent ductus arteriosus (sPDA). In addition prolonged indomethacin therapy was int