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Effects of growth factors on cell proliferation and monoclonal antibody production of batch hybridoma cultures

โœ Scribed by Girish J. Pendse; James E. Bailey

Publisher
Springer Netherlands
Year
1990
Tongue
English
Weight
259 KB
Volume
12
Category
Article
ISSN
0141-5492

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A quantitative study of the influence of initial serum concentration on hybridoma growth rate, maximum viable and total cell yield, and specific antibody production rate is presented. The specific growth rate varied in a Monod fashion with initial serum levels (2-10ยฐ/0 FCS), giving K,,, = 1.6 v/v% a