Effects of grapefruit juice on the multidrug transporter P-glycoprotein in the human proximal tubular cell line HK-2
β Scribed by Nadia Romiti; Gianfranco Tramonti; Andrea Donati; Elisabetta Chieli
- Book ID
- 116717612
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- English
- Weight
- 393 KB
- Volume
- 76
- Category
- Article
- ISSN
- 0024-3205
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## Abstract HKCβ8 cells are a humanβderived renal proximal tubular cell line and provide a useful model system for the study of human renal cell function. In this study, we aimed to determine [Ca^2+^]~i~ signalling mediated by P2 receptor in HKCβ8. Furaβ2 and a ratio imaging method were employed to