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Effects of glucocorticoid treatment on bone strength

✍ Scribed by Andrew S. Manolides; Diane M. Cullen; Mohammed P. Akhter

Book ID
106231226
Publisher
Springer
Year
2010
Tongue
English
Weight
197 KB
Volume
28
Category
Article
ISSN
0914-8779

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## Abstract Glucocorticoid therapy is the most common cause of secondary iatrogenic osteoporosis. The bone loss occurs predominantly due to a decrease in bone formation, although increased bone resorption also occurs. Glucocorticoids induce osteoblast apoptosis and increase osteoclast survival and