Transport of valganciclovir, a ganciclov
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Mitsuru Sugawara; Wei Huang; You-Jun Fei; Frederick H. Leibach; Vadivel Ganapath
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Article
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2000
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John Wiley and Sons
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English
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In clinical trials, valganciclovir, the valyl ester of ganciclovir, has been shown to enhance the bioavailability of ganciclovir when taken orally by patients with cytomegalovirus infection. We investigated the role of the intestinal peptide transporter PEPT1 in this process by comparing the interac