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Effects of glibenclamide on glycylsarcosine transport by the rat peptide transporters PEPT1 and PEPT2

โœ Scribed by Kyoko Sawada; Tomohiro Terada; Hideyuki Saito; Yukiya Hashimoto; Ken-ichi Inui


Book ID
110004633
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
244 KB
Volume
128
Category
Article
ISSN
0007-1188

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Transport of valganciclovir, a ganciclov
โœ Mitsuru Sugawara; Wei Huang; You-Jun Fei; Frederick H. Leibach; Vadivel Ganapath ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 231 KB

In clinical trials, valganciclovir, the valyl ester of ganciclovir, has been shown to enhance the bioavailability of ganciclovir when taken orally by patients with cytomegalovirus infection. We investigated the role of the intestinal peptide transporter PEPT1 in this process by comparing the interac