Effects of fluoride on sugar phosphate phosphohydrolase from escherichia coli and neisseria meningitidis
โ Scribed by Brad W.C. Lau; Ya-Pin Lee
- Book ID
- 103119883
- Publisher
- Elsevier Science
- Year
- 1982
- Tongue
- English
- Weight
- 356 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0020-711X
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Based on primary amino acid sequence comparisons with other phosphoglucomutases, 12 conserved residues in the Acetobacter xylinum phosphoglucomutase (CelB) were substituted by site-directed mutagenesis, resulting in mutant enzymes with K cat values [glucose-1phosphate (G-1-P) to glucose-6-phosphate]
## Abstract Asparaginases isolated from __Escherichia coli__ and __Erwinia carotovora__ are effective in the treatment of acute lymphoblastic leukemia in man. During treatment with either of these enzymes, patients frequently experience pronounced toxicity, including liver and pancreatic dysfunctio