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Effects of exposure to standard- and nicotine-reduced-cigarette smoke on pharmacokinetics of theophylline and cimetidine in rats

โœ Scribed by Yutaka Gomita; Kohei Eto; Katsushi Furuno; Yasunori Araki


Publisher
John Wiley and Sons
Year
1992
Tongue
English
Weight
526 KB
Volume
81
Category
Article
ISSN
0022-3549

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Influences of acute exposure to cigarette smoke on plasma concentrations of nicorandil administered orally and parenterally were investigated in rats by HPLC. The animals were exposed to tobacco smoke of two kinds of cigarettes using a smoking machine (i.e., the cigarette smoke contained either low