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Effects of epidermal growth factor, fibroblast growth factor, retinoic acid and serum on anchorage-dependent and anchorage-independent growth of HRRT cells

โœ Scribed by Eker, Per

Book ID
122081876
Publisher
Elsevier Science
Year
1989
Weight
600 KB
Volume
25
Category
Article
ISSN
0277-5379

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Anchorage-independent growth, i.e., growth in semi-solid medium is considered a marker of cellular transformation of fibroblast cells. Diploid human fibroblasts ordinarily do not exhibit such growth but can grow transiently when medium contains high concentrations of fetal bovine serum. This suggest