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Effects of endothelins on morphological changes in cultured astrocytes

✍ Scribed by Koyama, Yutaka; Baba, Akemichi

Book ID: 122405904
Publisher: Elsevier Science
Year: 1991
Weight: 104 KB
Volume: 16
Category: Article
ISSN: 0921-8696
DOI: 10.1016/0921-8696(91)90755-C

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## Abstract The astrocytic endothelin (ET) receptors, ET~A~ and ET~B~, modulate calcium signaling and the astrocytic gap junctional network. The nonselective ET receptor ligand ET‐1 inhibits gap junction permeability, an effect that can be blocked by tolbutamide. This mechanism may play a role in p