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Effects of endogenous β-amyloid overproduction on tau phosphorylation in cell culture

✍ Scribed by Ze-Fen Wang; Hong-Lian Li; Xia-Chun Li; Qi Zhang; Qing Tian; Qun Wang; Huaxi Xu; Jian-Zhi Wang


Book ID
111179658
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
631 KB
Volume
98
Category
Article
ISSN
0022-3042

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## Abstract Neuropathological studies have demonstrated that the presence of neurofibrillary tangles (NFTs) is one of the most prominent pathologic characteristics of Alzheimer's disease (AD). The microtubule‐associated protein tau is the major component of NFTs, and its abnormal hyperphosphorylati