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Effects of endocytosis inhibitors on internalization of human IgG by Caco-2 human intestinal epithelial cells

โœ Scribed by Koya Sato; Junya Nagai; Naoko Mitsui; Ryoko Yumoto; Mikihisa Takano

Book ID
116719702
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
470 KB
Volume
85
Category
Article
ISSN
0024-3205

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## Abstract Protein kinase C (PKC) isoforms are altered in colon tumors and upon exposure of intestinal mucosa to nutrients. We evaluated the effects of the PKC inhibitors staurosporine and calphostin C on human Cacoโ€2 intestinal epithelial proliferation, motility, and differentiation. Motility was