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Effects of Elevated pCO2 and Osmolality on Growth of CHO Cells and Production of Antibody-Fusion Protein B1: A Case Study

โœ Scribed by Marie M. Zhu; Asti Goyal; Douglas L. Rank; Sunil K. Gupta; Thomas Vanden Boom; Steven S. Lee

Book ID
109387130
Publisher
American Institute of Chemical Engineers
Year
2008
Tongue
English
Weight
217 KB
Volume
21
Category
Article
ISSN
8756-7938

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Effects of elevated pCO2 and/or osmolali
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โœ Roy Kimura; William M. Miller ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 849 KB

Carbon dioxide is a by-product of mammalian cell metabolism that will build up in culture if it is not removed from the medium. Increased carbon dioxide levels are generally not a problem in bench-top bioreactors, but inhibitory levels can easily be reached in large-scale vessels, especially if the