𝔖 Bobbio Scriptorium
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Effects of Divalent Metal Ions on Individual Steps of the Tetrahymena Ribozyme Reaction †

✍ Scribed by McConnell, Timothy S.; Herschlag, Daniel; Cech, Thomas R.

Book ID
126898114
Publisher
American Chemical Society
Year
1997
Tongue
English
Weight
231 KB
Volume
36
Category
Article
ISSN
0006-2960

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Inversion of configuration at phosphorus during ribozyme-catalyzed cleavage of RNA is usually considered unequivocal proof of in-line attack, but the relevant pseudorotation diagram for formation of the 2('),3(')-cyclic phosphate shows that inversion is not inconsistent with adjacent attack as long