Effects of deuterium on the thermal transition of nucleic acids
โ Scribed by Mahler, H.R.; Dutton, Gary; Mehrotra, B.D.
- Book ID
- 122388805
- Publisher
- Elsevier Science
- Year
- 1963
- Weight
- 669 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0926-6550
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๐ SIMILAR VOLUMES
A fully automatized apparatus for studying the spectrophotometer-monitored thermal transition of nucleic acids is described. Measurements are made with improved accuracy over standard methods, under thermodynamically well-defined conditions (thermal and phase equilibrium). Examples of highly resol
## Abstract __Intercalating nucleic acids (INAยฎs) with insertions of (__R__)โ1โ__O__โ(1โpyrenylmethyl)glycerol were hybridized with locked nucleic acids (LNAs). INA/LNA duplexes were found to be less stable than the corresponding DNA/LNA duplexes when the INA monomer was inserted as a bulge close t