A human eosinophilic leukemia cell line, EoL-1. stopped proliferating at the GI phase, differentiated into eosinophilic granule-containing cells, and died by apoptosis when stimulated with dibutyryl cyclic AMP (dbcAMP). To clarify the effects of dbcAMP, the effects of butyrate and CAMP-increasing re
Effects of cyclic AMP on expression of LFA-1, Mac-1, and VLA-4 and eosinophilic differentiation of a human leukemia cell line, EoL-1
β Scribed by Eun-Young Jung; Yusei Ohshima; Noriaki Shintaku; Shin-Ichi Sumimoto; Toshio Heike; Kenji Katamura; Mitsufumi Mayumi
- Book ID
- 114791826
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 649 KB
- Volume
- 53
- Category
- Article
- ISSN
- 0902-4441
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Migration of eosinophil (Eo) into tissues is a hallmark of chronic eosinophilic leukaemia (CEL), but the exact mechanism involved in cell migration is unknown. We report on a patient with CEL who presented high expressions of VLA-4, LFA-1 and Mac-1 integrins on the Eo surface, increased chemotaxis o
## Abstract We examined the expression of eosinophilic granules, esterase activity and CD14 in a human eosinophilic cell line, EoLβ1. Unstimulated EoLβ1 cells were weakly positive for nonspecific esterase, but negative for surface CD14, and contained a few eosinophilic granuleβpositive cells. A com