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Effects of copper and ceruloplasmin on iron transport in the Caco 2 cell intestinal model

✍ Scribed by Nora R. Zerounian; Maria C. Linder


Book ID
108473950
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
217 KB
Volume
13
Category
Article
ISSN
0955-2863

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The transport of 10 amino acid ester prodrugs of levovirin (LVV) was investigated in the human intestinal Caco-2 cell line in order to overcome the poor oral bioavailability of LVV, an investigational drug for the treatment of hepatitis C infection. The prodrugs were designed to improve the permeabi