✦ LIBER ✦

Effects of concomitant fluvoxamine on the metabolism of alprazolam in Japanese psychiatric patients: interaction with CYP2C19 mutated alleles

✍ Scribed by Yutaro Suzuki; Toshiki Shioiri; Tatsuyuki Muratake; Yoshiaki Kawashima; Satoshi Sato; Mieko Hagiwara; Yoshimasa Inoue; Kazutaka Shimoda; Toshiyuki Someya

Publisher: Springer
Year: 2003
Tongue: English
Weight: 197 KB
Volume: 58
Category: Article
ISSN: 0031-6970
DOI: 10.1007/s00228-003-0563-9

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Effect of smoking and CYP2D6 polymorphis

Effect of smoking and CYP2D6 polymorphisms on the extent of fluvoxamine–alprazolam interaction in patients with psychosomatic disease

✍ Hideyo Sugahara; Chiharu Maebara; Hisakazu Ohtani; Masanori Handa; Katsumi Ando; 📂 Article 📅 2009 🏛 Springer 🌐 English ⚖ 146 KB

Effect of the cytochrome P450 2D6*10 all

Effect of the cytochrome P450 2D6*10 allele on risperidone metabolism in Japanese psychiatric patients

✍ Yutaro Suzuki; Naoki Fukui; Nobuto Tsuneyama; Junzo Watanabe; Shin Ono; Takuro S 📂 Article 📅 2012 🏛 John Wiley and Sons 🌐 English ⚖ 79 KB

Objective The sum of the serum levels of risperidone (RIS) and 9-hydroxyrisperidone (9-OH-RIS), which is the active moiety serum level, could be important for estimating the clinical effects of RIS. However, there have been no consistent results reported about the relationship between cytochrome P45

Effects of the CYP2D6*10 alleles and co-

Effects of the CYP2D6*10 alleles and co-medication with CYP2D6-dependent drugs on risperidone metabolism in patients with schizophrenia

✍ Tatsuhiko Yagihashi; Masafumi Mizuno; Bun Chino; Yuji Sato; Kei Sakuma; Toru Tak 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 121 KB

## Abstract ## Objective Risperidone is converted to 9‐hydroxyrisperidone by CYP2D6. Two parameters were used to examine the influences of CYP2D6 polymorphism and of co‐medication on risperidone metabolism: the risperidone:9‐hydroxyrisperidone concentration ratio (R:9‐OHR ratio) and the sum of the