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Effects of Cisplatin on Mitochondrial Function in Jurkat Cells

✍ Scribed by Tacka, Kirk A.; Dabrowiak, James C.; Goodisman, Jerry; Penefsky, Harvey S.; Souid, Abdul-Kader

Book ID
120239628
Publisher
American Chemical Society
Year
2004
Tongue
English
Weight
192 KB
Volume
17
Category
Article
ISSN
0893-228X

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## Abstract The effects of cis‐diamminedichloroplatinum (11) (cisplatin), a drug used in cancer chemotherapy, on the oxidative metabolism, endocytosis, chemotaxis and exocytosis of guinea‐pig polymorphonuclear leukocytes were studied. All these functions were negatively influenced, but the same eff