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Effects of charge density and hydrophobicity of poly(amido amine)s for non-viral gene delivery

โœ Scribed by Martin Piest; Johan F.J. Engbersen

Book ID
113693482
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
391 KB
Volume
148
Category
Article
ISSN
0168-3659

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๐Ÿ“œ SIMILAR VOLUMES

Poly(amido amine)s as Gene Delivery Vect
Poly(amido amine)s as Gene Delivery Vectors: Effects of Quaternary Nicotinamide Moieties in the Side Chains
โœ Miguelโ€…A. Mateos-Timoneda; Martinโ€…C. Lok; Wimโ€…E. Hennink; Jan Feijen; Johanโ€…F.โ€…J ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 396 KB

## Abstract To evaluate the effect of quaternary nicotinamide pendant groups on gene delivery properties, a series of poly(amido amine) (co)polymers were synthesized by Michael addition polymerization of N, Nโ€ฒโ€cystaminebisacrylamide with variable ratios of 1โ€(4โ€aminobutyl)โ€3โ€carbamoylpyridinium (Ni