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Effect of chemical functionalities in poly(amido amine)s for non-viral gene transfection

โœ Scribed by Chao Lin; Johan F.J. Engbersen


Book ID
113691795
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
602 KB
Volume
132
Category
Article
ISSN
0168-3659

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Poly(amido amine)s as Gene Delivery Vect
โœ Miguelโ€…A. Mateos-Timoneda; Martinโ€…C. Lok; Wimโ€…E. Hennink; Jan Feijen; Johanโ€…F.โ€…J ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 396 KB

## Abstract To evaluate the effect of quaternary nicotinamide pendant groups on gene delivery properties, a series of poly(amido amine) (co)polymers were synthesized by Michael addition polymerization of N, Nโ€ฒโ€cystaminebisacrylamide with variable ratios of 1โ€(4โ€aminobutyl)โ€3โ€carbamoylpyridinium (Ni