𝔖 Bobbio Scriptorium
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Effects of calmodulin inhibitors on rabbit synoviocyte phospholipase A2

✍ Scribed by Ralph J. Rothenberg


Book ID
113301915
Publisher
Elsevier Science
Year
1987
Weight
568 KB
Volume
29
Category
Article
ISSN
0262-1746

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A simple synthesis of biaryl phospholipa
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A series of biaryl acids has been synthesized by treating diphenic anhydride with a variety of amines. The one step strategy allows the rapid interchange of groups for evaluating the hydrophobic constraints of inhibitors of phopholipase A2. The most active inhibitor synthesized displayed an IC50 = 6