Effect of a novel calcium antagonist AE0
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Katsumi Yamanaga; Yutaka Ohtaki; Takeshi Uchida; Masahiro Watanabe
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Article
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1992
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John Wiley and Sons
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English
โ 496 KB
We examined the cerebral protective effects of AE0047 employing cerebral ischemia models. In the bilateral carotid arterial occlusion model (BCAO) employing spontaneously hypertensive rats (SHRs), oral administration of AE0047 (0.1-0.3 mg/kg) or nicardipine (3 mg/kg) improved the neurological sympto