Effects of cadmium on the release of tissue plasminogen activator and plasminogen activator inhibitor type 1 from cultured human vascular smooth muscle cells and fibroblasts
โ Scribed by Chika Yamamoto; Toshiyuki Kaji; Michiko Sakamoto; Hiroshi Kozuka
- Book ID
- 107939017
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 649 KB
- Volume
- 106
- Category
- Article
- ISSN
- 0300-483X
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## Abstract Increased expression of plasminogen activator inhibitor type 1 (PAIโ1) is associated with decreased apoptosis of neoplastic cells. We sought to determine whether PAIโ1 alters apoptosis in vascular smooth muscle cells (VSMC) and, if so, by what mechanisms. A twofold increase in the expre
The effects were examined of baicalein on tissue-type plasminogen activator (t-PA) and plasminogen activator inhibitor-1 (PAI-1) production stimulated by interleukin-1โฃ (IL-1โค) and tumour necrosis factor-โฃ (TNF-โฃ) in cultured human vein umbilical endothelial cells (HUVECs). IL-1โค and TNF-โฃ increased