𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Effects of buffer composition and processing conditions on aggregation of bovine IgG during freeze-drying

✍ Scribed by Jeanne-Marie Sarciaux; Said Mansour; Michael J. Hageman; Steven L. Nail

Book ID
109389205
Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
185 KB
Volume
88
Category
Article
ISSN
0022-3549

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Effects of solution conditions, processi
Effects of solution conditions, processing parameters, and container materials on aggregation of a monoclonal antibody during freeze–thawing
✍ Lisa A. Kueltzo; Wei Wang; Theodore W. Randolph; John F. Carpenter πŸ“‚ Article πŸ“… 2008 πŸ› John Wiley and Sons 🌐 English βš– 178 KB

Freeze-thawing is a potentially damaging stress to which therapeutic proteins can be exposed deliberately during storage of bulk drug substance, and accidentally because of mishandling of commercial product during shipping and/or storage. The primary route of degradation induced by freeze-thawing is