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Effects of biological DNA precursor pool asymmetry upon accuracy of DNA replication in vitro

✍ Scribed by Stella A Martomo; Christopher K Mathews

Book ID
114070536
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
266 KB
Volume
499
Category
Article
ISSN
0027-5107

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Both the polymerase and the exonuclease activities of DNA polymerase III are inactivated by treatment with nitrosoguanidine. The treatment of the DNA template with the mutagen does not affect the template in supporting DNA synthesis. No effect of nitrosoguanidine upon fidelity of replication in vitr