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Effects of beta-amyloid oligomers on neuronal viability and microglial activation

โœ Scribed by Denise Ferrera; Claudio Canale; Fabio Benfenati; Laura Gasparini


Book ID
118464806
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
45 KB
Volume
5
Category
Article
ISSN
1552-5260

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Amyloid โค-protein (Aโค), the major component of plaques in Alzheimer's disease, is a small hydrophobic protein that is carried on apolipoprotein E (ApoE)-and ApoJ-containing lipoprotein particles in plasma and cerebrospinal fluid (CSF). Microglia, the scavenger cells of the CNS, take up and degrade A