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Effects of atenolol and propranolol on human performance and subjective feelings

✍ Scribed by A. A. Landauer; D. A. Pocock; F. W. Prott


Publisher
Springer
Year
1979
Tongue
English
Weight
481 KB
Volume
60
Category
Article
ISSN
0033-3158

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✦ Synopsis


In a double-blind, double crossover experiment, 18 healthy young men received over 3-day periods either I00 nag atenolol, 80 mg propranolol, or placebo. The subjects underwent various motor and cognitive tests 18 h after each last dose had been taken. Propranolol significantly increased variability of a choice reaction-time task. Scores on various subjective rating scales showed that propranolol had a Iarger mood elevating effect than atenolol. Heart rate and blood pressure were significantly reduced 24h after atenolol medication; these effects were absent or reduced after propranolol had been given.


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