Effects of atenolol and propranolol on human performance and subjective feelings
β Scribed by A. A. Landauer; D. A. Pocock; F. W. Prott
- Publisher
- Springer
- Year
- 1979
- Tongue
- English
- Weight
- 481 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0033-3158
No coin nor oath required. For personal study only.
β¦ Synopsis
In a double-blind, double crossover experiment, 18 healthy young men received over 3-day periods either I00 nag atenolol, 80 mg propranolol, or placebo. The subjects underwent various motor and cognitive tests 18 h after each last dose had been taken. Propranolol significantly increased variability of a choice reaction-time task. Scores on various subjective rating scales showed that propranolol had a Iarger mood elevating effect than atenolol. Heart rate and blood pressure were significantly reduced 24h after atenolol medication; these effects were absent or reduced after propranolol had been given.
π SIMILAR VOLUMES
The aim of the present study was to evaluate the central effects of single doses of the fi-adrenoceptor antagonist atenolol and the calcium antagonist nifedipine retard, alone and in combination, in normal subjects. Twelve normal males received single oral doses of atenolol 100 rag, nifedipine retar
## Abstract The lipophilic betaβadrenoreceptor antagonist propranolol and hydrophilic atenolol have been studied to define their pharmacokinetic and pharmacodynamic characteristics in obese patients. A total of 43 subjects were allocated into three study groups: (1) healthy, lean, normolipaemic vol