Effects of armagnac extracts on human platelet function in vitro and on rat arteriovenous shunt thrombosis in vivo
β Scribed by Anwar Umar; Viviane Guerin; Martine Renard; Michel Boisseau; Charles Garreau; Bernard Begaud; Mathieu Molimard; Nicholas Moore
- Book ID
- 117257545
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 175 KB
- Volume
- 110
- Category
- Article
- ISSN
- 0049-3848
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An improved plasma clot culture system was developed for the culture of rat megakaryocyte colonies in vitro. Greater stimulation of megakaryocyte colony growth was provided when both serum and plasma were added to the culture medium than when plasma was added alone. Freeze-thawed extracts prepared f
## Abstract We examined the antithrombotic effect of recombinant human soluble thrombomodulin (rhsβTM) using an arteriovenous shunt thrombosis model and its influence on hemostasis in rats. Intravenous administration of rhsβTM (0.5β4 mg/kg) significantly inhibited thrombus formation and prolonged e