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Effects of an opiate on cold-induced pain and the CNS in healthy volunteers

✍ Scribed by Posner, John; Telekes, Andras; Crowley, Dominic; Phillipson, Richard; Peck, Anthony W.


Book ID
122089613
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
738 KB
Volume
23
Category
Article
ISSN
0304-3959

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Two double blind cross-over studies were performed using a submaximal effort tourniquet test (SETT) in healthy volunteers to investigate the role of endogenous opioids in placebo analgesia. In the first study IV naloxone significantly inhibited analgesia, miosis and sedation produced by the opioid d