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Effects of an inhibitor of cathepsin L on bone resorption in thyroparathyroidectomized and ovariectomized rats

✍ Scribed by A.J. Millest; S.A. Breen; B.E. Loveday; P.N. Clarkson; C.A. Simpson; J.C. Waterton; D. Johnstone


Book ID
119650737
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
630 KB
Volume
20
Category
Article
ISSN
8756-3282

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To determine whether the uterus plays any role in mediating the ability of estrogen to conserve bone in the rat, eight groups of animals (n = 8) with their skeletons labeled with 45Ca were studied. Rats were ovariectomized (OVX), hysterectomized (Hyst), or given sham operations (Sham) and then pair-