Effects of amputation and Corynebacterium parvum on tumour metastases in mice
β Scribed by Mosley, J G; Sadler, T E; Castro, J E
- Book ID
- 109833863
- Publisher
- Nature Publishing Group
- Year
- 1978
- Tongue
- English
- Weight
- 667 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0007-0920
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## Abstract The effects of __Corynebacterinm parvum__ and cortisone acetate (CA) on the primary Lewis lung carcinoma and its pulmonary metastases were investigated. __C. parvum__ given IV either on the same day or 7 days after tumour inoculation, reduced primary tumour growth, while 2.5 mg CA (high
## Abstract The natural resistance to syngeneic mammary carcinoma was reduced by thymectomy alone in adult C~3~H mice or in mice thymectomized, lethally irradiated and restored with boneβmarrow cells (Tx RB). The protective effect of __C. parvum__ was not modified by adult thymectomy but it was red
## Abstract The effects of Corynebacterium parvum on the mouse primary Lewis lung carcinoma and its metastases were studied. C. parvum was given at the same time as subcutaneous inoculation of tumour or in combination with surgical excision of the primary after 10 days' growth. When intravenous C.