Effects of amiodarone administration during pregnancy in Fischer 344 rats
โ Scribed by Dwayne A. Hill; Mark J. Reasor
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 606 KB
- Volume
- 65
- Category
- Article
- ISSN
- 0300-483X
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A single dose of 40 mg/kg of N-nitrosoethylurea (ENU) was administered to BDVI rats on the 16th day of pregnancy. The first generation descendants (F1) were mated on a brother-to-sister system to produce a second generation (F2) which was then mated to produce a third generation. A high incidence of
## Abstract Killed Corynebacterium parvum vaccine was infiltrated into growing subcutaneous tumors (two antigenically different types) syngeneic to the Fischer 344 rats. In all these animals decrease in tumor size was followed by total and lasting disappearance. The protective response conferred as