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Effects of amiloride on intracellular pH and thermosensitivity

โœ Scribed by Gwi E Kim; John C Lyons; Chang W Song

Book ID
107964103
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
996 KB
Volume
20
Category
Article
ISSN
0360-3016

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Amiloride and DIDS (4,4-diisothiocyanato-stilbene-2,2 '-disulfonic acid) have been used to lower intracellular pH and increase thermosensitivity of malignant cells. We previously observed adverse reactions after injection of these drugs in canines and hypothesized that reactions may be mediated by a