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Effects of alpha-difluoromethyl ornithine on alphafetoprotein and albumin secretion in human hepatoma cell line, PLC/PRF/5

✍ Scribed by Nakagawa, Toshitaro; Nakao, Yoshinobu; Matsui, Toshimitus; Koizumi, Tamio; Watanabe, Shaw; Fujita, Takuo


Book ID
123271926
Publisher
Elsevier Science
Year
1985
Tongue
English
Weight
472 KB
Volume
28
Category
Article
ISSN
0304-3835

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## Abstract The __in vitro__ effect of sodium butyrate (SB) on human hepatoma cell lines PLC/PRF/5, HCC‐M and HCC‐T was investigated. SB was added at the non‐toxic but cytostatic concentration of I mM. In all these cell lines, SB reduced cell proliferation and changed the morphology of the cells in