A procedure is described which yields a significant percentage of long-term mixed cell cultures of human prostatic tissue. Attempts were made to suppress the proliferation of stromal fibroblasts and to characterize the cultured cells as those of prostatic origin. The problems associated with establi
Effects of aldosterone antagonists on organ cultures of human prostatic tissue
โ Scribed by J. E. Castro; R. A. Sellwood
- Publisher
- John Wiley and Sons
- Year
- 1974
- Tongue
- English
- Weight
- 491 KB
- Volume
- 113
- Category
- Article
- ISSN
- 0022-3417
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## BACKGROUND. A variety of hormones have demonstrated effects on prostatic tissue growth dynamics. Our goal was to define the effect of dihydrotestosterone (DHT), epidermal growth factor (EGF), and prolactin (PRL) on prostate cellular proliferation. METHODS. Thirty benign human prostatic hyperpla