## Abstract The prostatic epithelium is functionally organized in stem cell units. This unit consists of a slow turn over stem cell within the basal epithelial layer which can replenish itself and provide progeny which differentiate down either a neuroendocrine or exocrine pathway. The maturation a
In vitro culture of human prostatic tissue
β Scribed by Sanford, E.J. ;Geder, L. ;Jones, R.E. ;Rohner, T.J. ;Rapp, F.
- Publisher
- Springer
- Year
- 1977
- Tongue
- English
- Weight
- 361 KB
- Volume
- 5
- Category
- Article
- ISSN
- 0300-5623
No coin nor oath required. For personal study only.
β¦ Synopsis
A procedure is described which yields a significant percentage of long-term mixed cell cultures of human prostatic tissue. Attempts were made to suppress the proliferation of stromal fibroblasts and to characterize the cultured cells as those of prostatic origin. The problems associated with establishing epithelial cell lines are discussed.
π SIMILAR VOLUMES
BACKGROUND. An in vitro model of prostatic stromal cells suitable for experimental studies of the pathogenesis of BPH is still lacking. We therefore standardized the isolation, cultivation, and characterization of human prostatic stromal cell lineages. METHODS. Stromal cells were isolated from a sur
Lactoferrin levels have been determined by radialimmunodiffusion in homogenates of both human benign prostatic hypertrophy obtained at open surgery from patients, some of whom had been treated with oestrogens or antiandrogens, and also in prostatic adenocarcinoma tissue removed by transurethral rese