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Effects of alcohol on serum fluphenazine levels in stable chronic schizophrenics

✍ Scribed by S. D. Soni; J. S. Bamrah; J. Krska

Publisher
John Wiley and Sons
Year
1991
Tongue
English
Weight
493 KB
Volume
6
Category
Article
ISSN
0885-6222

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✦ Synopsis

Seven chronic schizophrenic patients, stable for over 12 months on maintenance fluphenazine decanoate, were administered 40 g of alcohol orally soon after their regular injection. Blood samples for estimation of serum neuroleptic and prolactin levels were collected at various intervals over a 12 h period. The procedure was repeated at their next regular injection but without alcohol. It was found that alcohol ingestion produced a significant drop in both serum neuroleptic and prolactin levels which persisted during the study period.

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