Effects of alcohol and solvent on the performance of lipase from Candida sp. in enantioselective esterification of racemic ibuprofen
β Scribed by Ying Liu; Fang Wang; Tianwei Tan
- Book ID
- 113804343
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 266 KB
- Volume
- 56
- Category
- Article
- ISSN
- 1381-1177
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The lipase-catalyzed enantioselective esterification of ibuprofen has been studied in a media, composed only of substrates. When racemic ibuprofen is used, the alcohol-chain length affects the esterification rates of individual enantiomers, but it does not affect the enantioselectivity. Water activi
Substituent effects on the enantioselectivity for the lipase-catalyzed esterifications in organic solvents were studied by use of 2-(4-substituted phenoxy)propionic acids as the substrates with various substituents of H, F, Cl, CF 3 , CH 3 , CH 3 CH 2 , and CH 3 O. The distinction in the behavior of