Effects of Additives on the Activity and Enantioselectivity of Candida rugosa Lipase in a Biphasic Medium
✍ Scribed by S. Salgın; S. Takaç
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 109 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0930-7516
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Semipurified lipase of Candida rugosa (CRSL) was subjected to chemical modification, and the activities of the modified lipase, in hydrolysis and esterification reactions, were examined. The esterification reactions were carried out in the absence and presence of isooctane. When the enzyme was modif
Lipase from Candida rugosa immobilized on a nylon support has been used to synthesize lovastatin, a drug which lowers serum cholesterol levels, by the regioselective acylation of a diol lactone precursor with 2methylbutyric acid in mixtures of organic solvents. Analogs of lovastatin having a differe