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Effects of aging on DNA-binding activity of the E47 transcription factor in splenic B cells

✍ Scribed by Daniela Frasca; Diep Nguyen; Richard L. Riley; Bonnie B. Blomberg

Book ID
113775624
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
60 KB
Volume
125
Category
Article
ISSN
0047-6374

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Inducible phosphorylation or dephosphorylation of transcription factors is an important mechanism of signal-dependent gene regulation in eukaryotic cells. This paper describes a combination of techniques that can be used to study the effect of this covalent protein modification on the DNA-binding ac