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Effects of aging and sediment composition on hexachlorobenzene desorption resistance compared to oral bioavailability in rats

โœ Scribed by Yunzhou Chai; John W. Davis; Shakil A. Saghir; Xiujin Qiu; Robert A. Budinsky Jr.; Michael J. Bartels

Book ID
116360310
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
178 KB
Volume
72
Category
Article
ISSN
0045-6535

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The enhancing effects of cyclodextrins (CyDs) on the solubility, the dissolution rate, and the bioavailability of tacrolimus after oral administration to rats were examined and compared with those after administration of a PROGRAF 1 capsule containing the solid dispersion formulation of tacrolimus.